General Cell Based Assays
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0709
PhosphoSens-Kinetic Kinase Activity Kit 1000 assays - AQT0709
Cayman Chemical L-(−)-Glucose, Purity: ≥95%, CAS: 921-60-8, 500 mg
An enantiomer D-glucose that is not bioavailable to cells as an energy source because it cannot be phosphorylated by hexokinase
Eurofins Discoverx PathHunter eXpress YES1 Activity Assay, 10-Plate Kit. (93-0883E3CP16L)
The PathHunter eXpress YES Activity Assay is a stable, engineered cell line for use in studying small molecule drug candidates targeting the YES kinase domain. The cell line is engineered to express the catalytic domain from YES fused to the cytokine receptor binding domain (CRBD) of JAK2. The cells co-express an Enzyme Acceptor (EA) tagged SH2 domain and a ProLink (PK) tagged Cytokine receptor. The CRBD is designed to bind the CTK catalytic domain to the GHR-PK. Activation of the GHR-PK induces receptor phosphorylation by the YES catalytic domain. This leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress NPY2R CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0212E2CP0M)
The PathHunter NPY2R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. peptide YY) based activation of NPY2R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged NPY2R and EA-tagged β-Arrestin-2. Activation of NPY2R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0420
PhosphoSens-Kinetic Kinase Activity Kit 1000 assays - AQT0420
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0794
PhosphoSens-Kinetic Kinase Activity Kit 1000 assays - AQT0794
Eurofins Discoverx SPRINTer™ Human CDKN1A (p21) Targeted Protein Degradation Cell-Based Assay Kit (HCT-116)
The SPRINTer™ Human CDKN1A (p21) Targeted Protein Degradation Stable Cell Line Assay (HCT-116) contains a stable clonal cell line used for monitoring drug-induced protein turnover of CDKN1A (p21), supporting TPD studies. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress IGF1R Functional Assay, 2-Plate Kit. (93-0505E1CP17M)
The PathHunter eXpress IGF1R Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated IGF1R dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged IGF1R and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0645
PhosphoSens-Kinetic Kinase Activity Kit 1000 assays - AQT0645
Eurofins Discoverx PathHunter Insulin Glargine Bioassay Kit, 10pl. (93-0466Y3-00012)
The PathHunter Insulin Glargine Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses insulin or insulin glargine based activation of INSRb RTK receptors via detection of SH2 domain protein recruitment. The included cell line overexpresses ProLink-tagged INSRb and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter Human OXGR1 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human OXGR1 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure OXGR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.